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Nitrofurantoin is an antibiotic used for treatment and prevention of urinary tract infections (e.g., acute cystitis, urethritis) and those caused by urologic surgery or examination (cystoscopy, catheterization). Absorbed well from the gut, Nitrofurantoin reaches its high concentration in the urine were it kills bacteria that cause the infections. Nitrofurantoin will not work for viral infections (e.g., common cold or flu); it should not be used to treat infections outside the bladder (e.g., pyelonephritis).

Nitrofurantoin should be taken at evenly spaced intervals, as it works best when the amount of medicine in your body is kept at a constant level. It should be taken with food or milk, usually twice a day, as prescribed by your doctor. It is very important to complete the full course, even if you get better after a shorter period. Nitrofurantoin may produce side effects and interfere with urine tests for glucose showing false positive result. It may color your urine, which is no cause for concern.